Anti-centromere antibodies in 2 patients with discoid lupus erythematosus and no signs of systemic sclerosis.

The cutaneous sequelae of burns are usually temporary loss of pigment, hypertrophic scar and keloid. Infrequently skin neoplasia such as squamous cell carcinoma, basal cell carcinoma, malignant melanoma and sarcoma develop within the burn scar. Because ILVEN was developed after a burn in our patient, it is suggested that the possible mechanism for the development of ILVEN may have been that the burn acted as a simple trauma or induced an impairment of the immune function which was responsible for the onset of ILVEN. ILVEN is typically resistant to various therapies including corticosteroids, tar, dithranol and cryotherapy (3, 4). The skin lesions in our patient also responded poorly to various therapies. There are several reports that topical calcipotriol is an e¡ective and safe therapy for the treatment of ILVEN (4, 5). Our patient was treated with topical calcipotriol twice a day for 5 months and showed marked improvement. REFERENCES